A condition where the thyroid gland does not produce enough thyroid hormones, causing fatigue, weight gain, cold intolerance, and mental sluggishness. More common in women and increases with age.
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InstantMed Clinical Team
AHPRA Registered · Reviewed 2026-04
Hypothyroidism is one of the most common endocrine conditions I manage, and levothyroxine is straightforward -- but getting the dose right requires patience. TSH changes take 6-8 weeks to stabilise after a dose adjustment, so checking levels too early leads to unnecessary dose changes and a 'chasing the number' pattern. The most common reasons for persistent symptoms despite treatment are: incorrect dose (check TSH), poor medication absorption (taking with food or coffee), iron or vitamin D deficiency (screen for these), and concurrent depression. I also see many patients requesting 'natural thyroid' preparations (desiccated thyroid extract). While some patients prefer these, they contain variable T3/T4 ratios and are harder to dose consistently. Levothyroxine is synthetic but identical to human T4 and is the standard of care endorsed by all major endocrine societies.
Levothyroxine replacement therapy is the standard treatment for hypothyroidism. The goal is to normalise TSH and relieve symptoms. Dosing is individualised based on weight, age, and TSH response. Most patients require lifelong treatment, though some with subclinical hypothyroidism may not need medication.
Eutroxsig, Eltroxin, Oroxine
Tertroxin
Hypothyroidism (Underactive Thyroid) in Australia
Typical recovery timeline and return-to-work guidance for most patients.
Typical recovery
Levothyroxine takes 4-6 weeks to reach steady state. Most patients notice improvement in energy and mood within 2-4 weeks of reaching the correct dose. Full symptom resolution may take 2-3 months. Some symptoms (dry skin, hair changes) take longer to resolve.
Return to work
Hypothyroidism rarely requires time off work. Severe fatigue at diagnosis may warrant a few days. Once on the correct dose, most people function normally. If fatigue persists despite normal TSH, investigate other causes.
When to reassess
TSH check 6-8 weeks after starting or changing dose. Once stable, annual TSH monitoring is sufficient. Recheck sooner if symptoms change, if pregnant or planning pregnancy, or if starting/stopping medications that affect thyroid absorption (iron, calcium, PPIs).
Evidence-based tips to support your recovery alongside medical treatment.
Answers to the most common questions from patients.
Real experiences from Australians who've used InstantMed
Individual experiences may vary. All requests are subject to doctor assessment.
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